Research

UK Clinical Eye Research Strategy

Building the trabecular outflow pathway on-a-chip to dissect the mechanism of aqueous outflow dysfunction in glaucoma

Investigating the neural mechanisms behind Charles Bonnet Syndrome

The study will investigate Charles Bonnet Syndrome (CBS) by providing an in-depth profile of the basic neurochemistry, structural and functional pathways of the visual brain in CBS.

Using genetic technology to improve understanding of Leber hereditary optic neuropathy (LHON)

Leveraging Functional Genomics to Understand Mitonuclear Combinations in Leber Hereditary Optic Neuropathy

Identification of novel genes involved in fovea formation

Identifying variants impacting non-coding regions of genes underpinning inherited retinal disease

Identifying variants impacting splicing of 5' and 3'UTRs and underpinning inherited retinal disease

The effect of the density and distribution of panretinal photocoagulation (PRP) laser on driving visual fields in people with diabetes

Characterising the retina and subsequent damage in a model of Mucopolysaccharidosis Type IIIC

Characterisation of Retinal Phenotype in HGSNAT-deficient mice (Mucopolysaccharidosis Type IIIC)

Developing a Patient Reported Outcome Measure (PROM) for inflammatory eye disease and validation of a novel approach for PROM content identification