Research

Characterisation of retinal development in a zebrafish model of Wolfram Syndrome

Addressing Barriers to Amblyopia Therapy

Inflammatory eye disease as a Canary in the Coal Mine for future autoimmune disease: combining genetic and other variables to enhance individual risk prediction

Developing a new model to study drusen formation

Modelling drusen formation in retinal pigment epithelial cells and investigating drug candidates to slow the progression of AMD.

Understanding a molecular mechanism as a cause of retinitis pigmentosa

Exploring the molecular mechanism of a new cause of autosomal dominant retinitis pigmentosa and potential therapies.

Optogenetic therapy with CRISPR-assisted activation of rhodopsin

Binocular vision, visual function and pupil dynamics in people living with dementia

Binocular vision, visual function and pupil dynamics in people living with dementia: exploring their relationships to rate of cognitive decline and structural changes within the brain

Investigating alternative genetic causes of Retinitis Pigmentosa

The aim of the project is to understand if alterations in a gene called ARL13B, are present in patients with retinitis pigmentosa (RP), and to characterise how those alterations affect retinal cells.

The role of mitochondrial dysfunction in healthy ageing within the eye