Research

CRISPR activation for inherited blindness

UCL researchers are using gene-editing technique CRISPRa to replace the damaged OPA1 gene which leads to blindness.

Genotype-phenotype study of CRB1-retinopathy

To improve understanding of the natural history (or progression) of inherited retinopathies caused by faults in the CRB1 gene.

Uncovering the link between arthritis and sight loss in children

Research will the hypothesis that uveitis development in Juvenile Idiopathic Arthritis (JIA) is driven by changes to B-cell function.

Developing special glasses for patients with keratoconus

The aim of the project is to develop spectacles to provide better acuity for keratoconus patients.

Antivirulence treatment for microbial keratitis

Targeting Exotoxin U with repurposed drugs to improve the clinical outcomes of Pseudomonas aeruginosa infections.

A transcriptomic analysis to identify novel genes involved in fovea formation

Identifying genetic causes leading to Keratitis infection in UK patients

The aim of the study is to determine whether different types of isolates respond differently to drugs used to prevent or treat Acanthamoeba infection.

Ocular tuberculosis: validation of a novel model to understand pathogenesis

Glycosylation of VEGF Receptors as Pathogenic Regulator of Retinopathies