Research
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Completed
November 2016 - April 2018
Retinal activity in autism, ADHD and Duchenne muscular dystrophy
A non-invasive measure of visual impairment in people with neurological disorders
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Completed
January 2017 - January 2018
Identifying children with juvenile idiopathic arthritis at risk of uveitis
Aiming to prevent a common cause of childhood blindness
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Active
October 2018 - May 2024
Investigating the role of SIGIRR in geographic atrophy type of age-related macular degeneration
Understanding why the loss of SIGIRR leads to uncontrolled inflammation in AMD.
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Completed
October 2018 - January 2022
Development of a cell therapy treatment for uveitis
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Completed
April 2018 - May 2019
Characterisation of novel neuronal receptors at human corneal limbus
Finding out the nature of nerve terminals using a variety of histological techniques. The results could shed light on the function of these structures and their role in relation to corneal sensation, stem cell mechanism and prevention of blindness.
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Completed
April 2018 - December 2019
Examination of the TrkB receptor signalling pathway throughout the retina of glaucoma patients versus age-matched controls.
This project will improve our understanding of BDNF signalling in human retinal tissue.
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Completed
January 2018 - July 2022
Targeting a receptor pathway for the prevention of retinal fibrosis in neovascular age-related macular degeneration
Researchers aim to understand whether the development of fibrosis in nAMD can be prevented by targeting the C5aR pathway.
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Completed
August 2017 - July 2021
Investigation and treatment of intronic ABCA4 mutations in patients with inherited retinal dystrophy
A proportion of the causative mutations include those that occur within introns of the gene.
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Completed
October 2017 - December 2019
Creation of bio-synthetic corneal endothelial grafts for transplantation
The expansion of corneal endothelial cells in the laboratory onto a suitable material will enable the creation of bio-synthetic endothelial grafts.