Research
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Completed
October 2018 - June 2022
Cell-cell junctions in retinal disease: The role of ARHGEF18/p114RhoGEF
Researchers aim to identify the molecular mechanisms by which defective p114RhoGEF leads to malfunctioning of cell-cell junctions in retinal pigment epithelial cells and photoreceptors, and how such defects lead to degeneration of these cell types.
2018 - 5071/5072 - Balda -
Active
September 2022 - January 2026
Genotype-phenotype study of CRB1-retinopathy
To improve understanding of the natural history (or progression) of inherited retinopathies caused by faults in the CRB1 gene.
2022 - 5165/GR001422 - Moosajee -
Active
May 2022 - May 2025
Identifying novel therapies for inherited eye disease
Investigating photoreceptor death which will act as a basis to identify novel therapies for inherited eye disease.
2022 - 5179/5180 - Megaw