Research
-
Cell-cell junctions in retinal disease: The role of ARHGEF18/p114RhoGEF
Researchers aim to identify the molecular mechanisms by which defective p114RhoGEF leads to malfunctioning of cell-cell junctions in retinal pigment epithelial cells and photoreceptors, and how such defects lead to degeneration of these cell types.
CompletedOctober 2018 - June 2022 -
Genotype-phenotype study of CRB1-retinopathy
To improve understanding of the natural history (or progression) of inherited retinopathies caused by faults in the CRB1 gene.
ActiveSeptember 2022 - January 2026 -
Identifying novel therapies for inherited eye disease
Investigating photoreceptor death which will act as a basis to identify novel therapies for inherited eye disease.
ActiveMay 2022 - May 2025