Research
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Completed
March 2017 - February 2018
How does laser therapy compare to eye drops for reducing pressure in the eye?
Finding out about how safe and effective the treatments are for people with glaucoma
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Completed
April 2018 - December 2019
Examination of the TrkB receptor signalling pathway throughout the retina of glaucoma patients versus age-matched controls.
This project will improve our understanding of BDNF signalling in human retinal tissue.
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Active
January 2018 - March 2024
Genetics of Advanced Glaucoma: Towards Predicting and Preventing Blindness
Identifying the best treatment option for patients who present with advanced glaucoma.
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Completed
October 2019 - December 2022
Targeting NAD+ for retinal ganglion cell protection in experimental glaucoma
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Active
April 2020 - March 2025
Understanding the genetic basis for steroid-induced eye pressure to develop personalised medicine
The aim is to develop a genetic test that will predict how a patient will respond to steroids, which are widely used to treat a range of eye conditions.
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Completed
January 2019 - September 2022
Promoting RGC survival and optic nerve regeneration by enhancing the axon transport of growth and survival receptors
Regeneration of the optic nerves may be able to restore vision to those blinded by optic nerve disease and eventually make eye transplants possible.
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Active
July 2021 - June 2024
Lifestyle determinants of intra-ocular pressure and glaucoma
Investigating the effect of a variety of lifestyle factors on eye pressure and the subsequent development of primary open angle glaucoma.
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Completed
December 2020 - December 2021
Investigating how brain-derived neurotrophic factor (BDNF) could prevent cell death in glaucoma
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Active
August 2022 - July 2025
miRNA-mediated therapy for the treatment of glaucoma
Investigating the role of micro RNA - thought to be an integral part of the disease mechanism in glaucoma - and explore its therapeutic potential for the condition through pre-clinical testing.